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PLLA Filler REVAGE V

$150.00

Minimize clogging during treatment with porous spherical particles with a smooth surface.

Estimated delivery 2024/05/30
Category:

What is PLA/PLLA ?
RolesofPLA/PLLA Fillers
Skin aging
Volume filling
Promote new tissue
formation and
collagen creation
Maintain natural
volume
Young skin
As the skin ages, the collagen, moisture and fat layers all decrease. PLA filler fills the lost volume and promotes
the production of collagen and living tissue.
• Moisture is absorbed at 1~2 weeks after injection, and the volume seems to decrease but the volume is
recovered after 4~8 weeks due to cell and collagen creation.
• Cells gradually enter the porous PLA to create collagen over time.
Before treatment.
Wrinkle and loss of face
volume due to aging
Wrinkled area are filled
with PLLA.
PLLA is absorbed / dissolved
in the body and the surface of
the skin is increased by PLLA
sphere, resulting in more skin
cells regerated.
The cells produced create
more collagen than before
the treatment, showing
natural wrinkle improvement
Mechanism
Skin Tissue Regeneration Collagen Regeneration
Comparison of Effects between HA and PLLA
● Increased secretion of growth factor (bFGF) that helps skin regeneration.
● TGI-beta signal is generated higher than other products, confirming that it is effective for skin cell growth
and regeneration.
● Confirmed that the collagen growth rate is higher than other products because a lot of fibroblasts are
generated in the skin.
HA Filler REVAGE V REVAGE R
Features
Image

Mechanism Fills the dermal layer Naturally filled by stimulating
collagen production
Naturally filled by stimulating
collagen production
Appearance Gel Sphere (freeze-dried) Powder (cake type with freeze-dried)
Ingredients Hyaluronic Acid Poly L-Lactic Acid (PLLA) with CMC PLLA + HA (80 : 20)
Timing of effect Immediately After 10 days After 3-4 days
Duration 6 ~ 10 months 18 ~ 24 months During 6 months
Recommended Session
(2022. in Korea) U$250 / 1 session U$1,700 / 3-4 sessions
with 4-6 weeks interval
U$1,700 / 3 sessions
With 4 weeks interval
Modification (Molding) YES NO partially YES
Market
Status
Market share 75% 10% 15%
Maturity Maturity → Decline Growth → Maturity Growth → Maturity
Growth Potential Low High Mid-High
※ HA fillers have a high reputation and a large number of customers, but in the red ocean market with keen price competition
※ Using HA fillers as a cash cow, and better to move to the PLLA market gradually
Comparison Matrix (HA Filler Vs. PLA Filler)
REVAGE – Name of our PLLA brand
Comparison Matrix (RevageV Vs. RevageR) Revage – Name of our PLLA brand
Description REVAGE V (Sphere type) REVAGE R (cake type)
1 Export License No. Medical Equipment Export No.22-630 Medical Equipment Export No. 22-631
2 Type of Product Tissue Repair Materials (PLLA Filler) Tissue Repair Materials (PLLA 필러) – Hybrid type of PLLA + HA
(Applicable as a cosmetic because it contains HA)
3 Particulate Structure
(Microscope)
Minimize clogging during treatment with porous
spherical particles with a smooth surface
Minimize clogging during treatment with porous
spherical particles with a smooth surface
4 Particle Size 25~50μm (25,000 ~ 40,000 dalton) 25~50μm (5,000 ~ 10,000 dalton)
5 Ingredients PLLA 150mg + CMC 50mg PLLA 40mg + Non cross-linked HA 10mg
6 Volume 200mg 50mg
7 Usage Autologous collagen booster that gives elasticity and volume effect Autologous collagen booster that gives elasticity and volume effect
8 Hydrating Hydrating dosage Sterile water for injection 6ml + Lidocaine 1ml (total 7ml) Sterile water for injection 6ml + Lidocaine 1ml (total 7ml)
Hydrating time 30 min – 2 hours (depending on room temperature) 30 min – 2 hours (depending on room temperature)
9 Lidocaine Adding Recommend to add 1ml of Lidocaine (see ‘saline dosage’ on No. 8) Recommend to add 1ml of Lidocaine (see ‘saline dosage’ on No. 8)
10 Injection Method Injection by hands (not recommendable injection device, like Potenza)
(Tip may become clogged due to the inclusion of CMC)
Injection by hands / Injection device like Potenza (both are applicable)
(Treatment with MTS 1.2mm or Potenza)
11 Injection Depth Subcutaneous injection Subcutaneous injection
12 Treatment Interval and Number 3-4 times at 4-6 week intervals 3 treatments at 1 month interval
13 Time to Take Effect After 10 days from treatment (currently in clinical trials) After 3-4 days from treatment (maximum effect after 1 month)
14 Duration 18 ~ 24 months 6 months
15 Cautions
(Rules of 5)
* Nose treatment is not recommended.
* After the procedure, request a 5-5-5 self-massage of the treated area
(not too strong) in a gentle circular shape (5 times a day, 5 minutes or
more, for 5 days) PLA spreads well, so the effect is better.
* Nose treatment is not recommended.
* After the procedure, request a 5-5-5 self-massage of the treated area
(not too strong) in a gentle circular shape (5 times a day, 5 minutes or
more, for 5 days) PLA spreads well, so the effect is better.
16 Storage No refrigeration. Store at room temperature below

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